How have animal models and mutations informed our understanding of nociception and possible new targets for analgesic drugs?

How have animal models and mutations informed our understanding of nociception and possible new targets for analgesic drugs?

Nociception is the body’s response to harmful or potentially harmful stimuli, this response occurs via the sensory nervous system. This process is typically initiated by the stimulation of nociceptors by intense chemical, mechanical or thermal interactions such as touching something hot or injury such as cutting of the skin??

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